Depression affects millions of people worldwide, and often the first treatment option offered is a drug, some form of antidepressant medication. For many people these drugs are effective (or effective enough), and they feel relief from the majority of their symptoms. But for many others, these traditional treatments don’t seem to work. This condition is known as treatment-resistant depression, and it is highly frustrating and debilitating for those who suffer from it.
Recognizing early signs of TRD is crucial to finding the correct treatment. In this article we will outline five key signs of TRD and what you can do to manage it.
Five signs of Treatment-Resistant Depression:
1. Lack of response to multiple antidepressants
If you’ve tried at least two antidepressant medications-taken at the correct dose and duration, but have experienced no relief from symptoms, you may be resistant to traditional medications. At that point alternative treatments such as Transcranial Magnetic Stimulation (TMS) or Spravato® (esketamine) may be required to improve symptoms.
2. Your symptoms persist despite therapy
Talk therapy, such as dialectical behavioral therapy is an important part of recovery and is effective for many both as a standalone treatment or in conjunction with medications. But if your symptoms remain severe despite consistent sessions you may need to combine it with a different approach.
3. Your Depression Significantly Impacts Your Daily Life
If your depression continues to interfere with your ability to work, maintain relationships, or engage in daily living tasks despite medication, it could indicate TRD.
4. Alternative Holistic Treatments Have No Perceptible Effect
Changing your lifestyle to include improved diet, exercise, and meditation can help with mild to moderate depression. But if these changes have not made a noticeable difference in your symptoms this could be another indicator of treatment-resistant depression.
4. Alternative Holistic Treatments Have No Perceptible Effect
Changing your lifestyle to include improved diet, exercise, and meditation can help with mild to moderate depression. But if these changes have not made a noticeable difference in your symptoms this could be another indicator of treatment-resistant depression.
5. Frequent Relapses After Previous Improvements
If you have previously experienced relief from treatments that is then followed by repeated depressive episodes, your condition may require a more specialized treatment intervention.
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What To Do If You Have TRD
Consider Alternative Treatments
- TMS Therapy: TMS is a non-invasive treatment that uses magnetic pulses to stimulate the areas of the brain that regulate mood.
- Spravato® (Esketamine): Spravato® is a fast-acting nasal spray effective for people with TRD.
Adjust Medication Strategy
Your psychiatric provider may suggest changes to your medication protocol such as switching medications, combining treatments, or adjusting medication dosages.
Incorporate Holistic Approaches
It is helpful to continue to exercise, eat a balanced diet, and practice mindfulness as a complement to your medical treatment.
Find Support Groups and Therapy
Connecting with others who are facing similar challenges can provide coping strategies and emotional support and help with feelings of isolation and frustration.
If you suspect you have TRD don’t lose hope, there are effective treatments available. At Oasis Mental Health Centers we specialize in advanced depression treatments. Contact us today to explore treatment options tailored to your needs.
