SPRAVATO TREATMENT IN ILLINOIS

Spravato® Treatment in Chicago, IL

FDA-approved esketamine nasal-spray therapy for adults with treatment-resistant depression — administered at our Chicago clinic with on-site monitoring.

  • TMS Available
  • Spravato®
  • Insurance Support
  • Private Treatment Spaces

Chicago at a Glance

Oasis Mental Health Centers in Chicago offers Spravato® treatment, an FDA-approved esketamine nasal spray for treatment-resistant depression, to patients in Chicago and surrounding areas.

Treatments Available

Spravato® is an FDA-approved esketamine nasal spray for treatment-resistant depression, administered with on-site monitoring by our care team. Oasis Mental Health Centers in Chicago offers it alongside TMS therapy, so you can review both options with a provider before deciding.

TMS therapy session

TMS therapy for depression

Targeted magnetic stimulation for treatment-resistant depression — drug-free and non-invasive.

Learn more →

Amenities

Free Coffee, Tea & Water

Power Outlets

Free Wi-Fi

Caregiver Waiting Areas

On-Site Parking

Private Treatment Spaces

Wheelchair Accessible

Public Transit Nearby

After-Hours Available

Languages Spoken

English
Spanish
Address
25 E Washington St
Suite 2001
Chicago, IL 60602
Hours
Monday to Friday, 9:00 AM to 5:00 PM

PROVIDERS

Meet the team at our Chicago office

Our Chicago team works closely with each patient to design a Spravato® treatment plan that fits.

Chicago Location Stats

Patients choose Oasis Chicago for Spravato® treatment in a private, supportive setting.

10
Google Reviews
2019
Opened
—
Patients Served
4
Treatment Rooms
—
TMS Treatments
—
Spravato® Treatments

Covered by major insurance providers

We work with the VA and accept most major insurance providers. Typical copays range from $5–$100 depending on your plan and treatment.

What to Expect Before Your First Appointment

Getting started with Oasis Chicago is simple.

  1. 01

    Book a consultation

    Start by requesting a consultation with the Oasis team.

  2. 02

    Share your basic information

    The team will collect the information needed to understand your treatment goals and insurance details.

  3. 03

    Review your treatment options

    Oasis will help determine whether TMS therapy, Spravato® treatment, or another care path may be appropriate.

  4. 04

    Confirm insurance coverage

    Your benefits will be reviewed before treatment begins, so you understand your coverage and next steps.

  5. 05

    Schedule your care

    If Oasis Chicago is the right fit, the team will help coordinate your appointment schedule.

If you're looking for TMS treatment in the downtown Chicago area I could not recommend a better place. The office is small but not stifling and the staff is incredible: kind, attentive, competent, understanding, and flexible. Any worries you have will be addressed immediately. As someone with social anxiety I was never anxious while there and the office is super easy to get to. I received treatment specifically for my long-term medication resistant depression and never left feeling overwhelmed or exhausted like I would have on any other outing. Please give this place a chance, I'm so glad I did.

Kylee Rather

Apr 4, 2025 · via Google

Scholarly sources estimate that the Milky Way galaxy has approximately 100 billion to 400 billion stars, but Google says the highest is 5 stars, so I'm leaving a 5 star review instead of a 400 billion star review. From the beginning, I felt that Dr. Rao immediately saw my deep suffering, listened to my own experience and analysis of my symptoms then used her expertise, experience and training to identify the root cause and, with my TMS tech Evelyn's help, provide effective treatment. Who knew that medicine can be transformative when you check your ego and your biases at the door and work WITH your patient to relieve their suffering? (The Mindful TMS staff knows this which is why I had a wonderful experience from beginning to end). While it hasn't been the miraculous, night and day treatment it can be for many, TMS helped kickstart the healing process after months of pain and hopelessness. TMS can take time to work but the small improvements add up over time in my experience. If you need relief quickly and have the means, consider pursuing the SAINT (Stanford Accelerated Intelligent Neuromodulation Therapy) TMS protocol which does 10 sessions per day for a total of 5 days instead of the 5x/week over 6 weeks in the standard rTMS protocol (Read T Kishi et al 2024's paper in Nature). From beginning to end, I was treated with kindness and respect by everyone at Mindful TMS. Evelyn and Dr. Rao are prime examples of professionalism and compassionate care thus Mindful TMS should be your first stop if you are considering pursuing TMS. Evelyn and Dr. Anita Rao need to be cloned, mass produced and deployed to lead every mental health clinic yesterday!

LBD

Aug 4, 2025 · via Google

I have had a wonderful experience at the chicago location of Mindful TMS. Marissa has been amazing - very gentle, attentive and careful. She is always sure to make sure everything is perfect and that you are comfortable before the treatment, during and after. I was nervous to start, but she answered all of my questions and eased my anxiety. I highly dexcom end this location - staff is great, facility is nice and clean. The chair and items are cleaned between use.

Bethany Petersen

Mar 26, 2021 · via Google

I have tried well over 10 medications for my anxiety and depression, and also attend therapy sessions weekly. Some meds were successful in keeping me out of bed during the day, but the side effects were never manageable. I even did GeneSight testing to help narrow down which meds might work best. Nothing seemed to be working for me and I was about to lose all hope until my psychiatrist referred me to Mindful TMS. Now I am nearing treatment number 30 and my mood has never been so stable. That horrible feeling of despair that has been with me every day since I was a child is gone. I am in the final year of my PhD at UChicago and my mental health has never been better! (I dare you to find another grad student who can say that.) My experience at Mindful TMS has been absolutely wonderful, and I owe it all to Aly my TMS therapist. She is incredibly welcoming, knowledgeable about all things TMS, and does a great job of making me feel comfortable and safe at all times. I genuinely look forward to coming in every morning to see Aly before I start the rest of my day. I strongly recommend Mindful TMS to anyone out there who is struggling - there are brighter days ahead of you!

Laura Lenart

Dec 21, 2021 · via Google

I cannot recommend Mindful TMS Chicago highly enough. The facility is pleasant and the staff: welcoming, efficient, accommodating, and professional. TMS has changed my life! I’ve tried many things, for 37 years, to be free of depression; but TMS is the only thing that has worked. Other things may have helped manage the depression, but TMS actually FREED me from it! If you suffer from depression or PTSD, DO try TMS. You owe it to yourself!

Dorothy Jackson

Apr 9, 2021 · via Google

FAQ

Common questions about Spravato® treatment in Chicago

Don’t see your question? Book a free consultation and we’ll walk you through it.

Does Oasis Chicago offer TMS therapy?

Yes. Oasis Mental Health Centers in Chicago offers TMS therapy for eligible patients with depression.

Does Oasis Chicago offer Spravato® treatment?

Yes. Oasis Chicago offers Spravato® treatment for eligible adults with treatment-resistant depression.

What are the Spravato® side effects?

The common side effects from Spravato® are dizziness, nausea, increased blood pressure, drowsiness, dissociation, and increased blood pressure.  These side effects often peak during or shortly after treatment and subside within a few hours. At Oasis Mental Health Centers, we ensure patient safety by administering Spravato® at REM’s certified locations, and under medical supervision in a comfortable setting.

How does Spravato® work?

Unlike traditional antidepressants that increase serotonin over weeks, Spravato® works on the NMDA receptor, targeting glutamate—a neurotransmitter responsible for mood regulation. This leads to rapid symptom relief, sometimes within hours. It helps form new neural connections, rewiring the brain to improve resilience.  Patients take Spravato® in-office twice a week for the first month, then less frequently based on progress.  

Does Spravato® cause weight gain?

Spravato® does not typically cause weight gain. Unlike some antidepressants that affect metabolism and appetite, Spravato®’s primary action is on glutamate pathways, which are not directly linked to weight changes. Some patients report minor appetite changes, but no significant weight gain has been documented in clinical trials. Unlike traditional antidepressants, it does not affect serotonin-related hunger signals.

Spravato® vs ketamine

Spravato® offers a safer, regulated approach to ketamine therapy. At Oasis Mental Health Centers, we provide only FDA approved and insurance covered Esketamine (Spravato®) treatment depression relief. Spravato® is the only version of Ketamine FDA approved, and covered by insurance for depression treatment.

Is Spravato® covered by insurance?

Yes! Every New Jersey based health insurer has a policy to cover Spravato®. Coverage depends on:

  • Your diagnosis – Must meet medical necessity criteria (varies by insurance, typically consists of at least 2 anti-depressant medication trials)
  • Your Copay or Coinsurance and deductible– Out-of-pocket costs vary depending on your insurance plan
  • Your insurer – Some plans require prior authorization.

    At Oasis Mental Health Centers, we help verify your insurance benefits and guide you through the approval process. Book a free consultation today to check your coverage!

What insurance does Oasis accept?

All New Jersey-based and most major insurance providers, including Medicare, Medicaid, Blue Cross Blue Shield, Aetna, Cigna, and UnitedHealthcare, cover both Spravato® and TMS for treatment-resistant depression when certain criteria are met. Coverage varies by plan and medical necessity requirements.

Do I need a referral?

Some patients may be referred by a provider; others may contact Oasis directly. The team can help you understand what's needed based on your insurance plan and treatment path.

How do I start depression treatment at Oasis Chicago?

The first step is to book a consultation. The Oasis team will review your information, discuss treatment options, and help verify your insurance benefits.

Can a caregiver wait during treatment?

Yes. Caregivers have space in the private treatment areas and rooms, and in the waiting area.

VISIT US

Serving Chicago & County

25 E Washington St, Suite 2001
Chicago, IL 60602
Phone: (312) 216-1211

Convenient parking, private treatment spaces, caregiver waiting areas, Wi-Fi and power outlets on site. Patients visiting for Spravato® treatment may need to arrange transportation home — the Oasis team will explain appointment requirements before treatment begins.

Patients Visit From
  • The Loop
  • River North
  • West Loop
  • South Loop
  • Streeterville
  • Lincoln Park
  • Near North Side
  • Near West Side

Book a free Spravato® consultation

If you’re exploring Spravato® treatment for treatment-resistant depression, Oasis Mental Health Centers in Chicago can walk you through the process.

Get clear answers about eligibility, insurance, scheduling, and what to expect.